Keynote opening lecture - Prothrombinase assembly and function- A story of blood and venom
James A. Huntington
                                        20:15h - 21:00h
                                    
                                
                                
 
                                    
                                        Opening of the conference
Boris Turk
                                        20:00h - 20:15h
                                    
                                
                                
 
                                    
                                        Closing of the conference
Boris Turk
                                        20:10h - 20:40h
                                    
                                
                                
 
                                    
                                        Targeting Cathepsin S using sharks and other animals    
Christopher Scott
                                        09:30h - 10:00h
                                    
                                
                                
 
                                    
                                        Cathepsin V regulates cell cycle progression and histone stability in the nucleus 
Roberta Burden
                                        09:30h - 09:45h
                                    
                                
                                
 
                                    
                                        Role of cathepsin X and γ-enolase in neuroinflammation: insights from models of multiple sclerosis 
Anja Pišlar
                                        09:30h - 09:45h
                                    
                                
                                
 
                                    
                                        Lung fibrosis: are cystatin M/E, cathepsin V and legumain newcorners in the game? 
Gilles Lalmanach
                                        09:30h - 10:00h
                                    
                                
                                
 
                                    
                                        SARS-CoV-2 spike protein affects receptor fates, proteases and the cytoskeleton of neurons 
Klaudia Brix
                                        11:30h - 12:00h
                                    
                                
                                
 
                                    
                                        Search for Inhibition of Cell Entry of SARS-CoV-2 and Other Viruses
Dušan Turk
                                        11:30h - 12:00h
                                    
                                
                                
 
                                    
                                        Cathepsin inhibitors in treatment of SARS-CoV-2 infection 
Janko Kos
                                        11:30h - 12:00h
                                    
                                
                                
 
                                    
                                        Heterogeneity of neutrophils based on the expression and activity of serine proteases 
Paulina Kasperkiewicz-Wasilewska
                                        14:30h - 15:00h
                                    
                                
                                
 
                                    
                                        DPP9 is a Positive Regulator of the Unfolded Protein Response
Ruth Geiss-Friedlander
                                        14:30h - 15:00h
                                    
                                
                                
 
                                    
                                        Human rhomboid protease RHBDL2 is a suppressor of EGFR signaling in keratinocytes 
Kvido Stříšovský
                                        14:30h - 15:00h
                                    
                                
                                
 
                                    
                                        Structural Evolution of Multiple Reactive Centers in Kunitz Inhibitors for Targeting Three Proteases 
Jaroslav Srp
                                        14:30h - 14:45h
                                    
                                
                                
 
                                    
                                        Mechanisms regulating caspase-1-mediated IL-1ß secretion: New insights into a longstanding question
Mohamed Lamkanfi
                                        09:00h - 09:30h
                                    
                                
                                
 
                                    
                                        The impact of ECM damage imprint in perpetuating chronic disease 
Irit Sagi
                                        09:00h - 09:30h
                                    
                                
                                
 
                                    
                                        Small molecule inhibitors of cytotoxic T cell killing as therapeutics for auto-immunity and immunopathology 
Joe Trapani
                                        09:00h - 09:30h
                                    
                                
                                
 
                                    
                                        Anti-inflammatory effect of cystatins is mediated by mTOR signaling 
Nataša Kopitar-Jerala
                                        09:00h - 09:15h
                                    
                                
                                
 
                                    
                                        Development of cathepsin B-selective antibody-drug conjugates supported by imaging mass cytometry 
Marcin Poręba
                                        11:30h - 12:00h
                                    
                                
                                
 
                                    
                                        Characterization of protease activities with conditionally activatable biologics 
Olga Vasiljeva 
                                        11:30h - 12:00h
                                    
                                
                                
 
                                    
                                        Directional Sandwich Panning to Select Inhibitory VHHs Against Fragile Enzymes Including Proteases 
Mireille Dumoulin
                                        11:30h - 11:45h
                                    
                                
                                
 
                                    
                                        NbE201: A single-domain antibody fragment to inhibit neutrophil elastase and reduce inflammation 
Paola Redeghieri
                                        11:30h - 11:45h
                                    
                                
                                
 
                                    
                                        Covalent reversible and irreversible compounds for selective detection and inhibition of cathepsin K
Galia Blum
                                        14:30h - 15:00h
                                    
                                
                                
 
                                    
                                        Aza-peptide Michael Acceptors as Inhibitors of the Human 20S Proteasome	 
Özlem Doğan Ekici
                                        14:30h - 15:00h
                                    
                                
                                
 
                                    
                                        Prion-Degrading Protease from Aeropyrum pernix K1
Nataša Poklar Ulrih
                                        14:30h - 15:00h
                                    
                                
                                
 
                                    
                                        Computational Studies on the Specificity of Substrate-Enzyme interactions based on MEROPS database 
Livija Tušar
                                        14:30h - 14:45h
                                    
                                
                                
 
                                    
                                        Processing and activation of IL-1 family cytokines by host and pathogen-associated proteases
Seamus J. Martin
                                        09:30h - 10:00h
                                    
                                
                                
 
                                    
                                        Miropin: The Yin and Yang of Tannerella forsythia Pathogenicity
Jan Potempa
                                        09:30h - 10:00h
                                    
                                
                                
 
                                    
                                        Generating cannibalistic appetites - a new role of P. gingivalis proteases
Juhi Bagaitkar
                                        09:30h - 10:00h
                                    
                                
                                
 
                                    
                                        The activator domain in bacterial collagenases unwinds triple-helical collagen
Johann Brandstetter
                                        11:30h - 12:00h
                                    
                                
                                
 
                                    
                                        How bacterial HtrA proteases interfere with epithelial host cells and control pathogenesis 
Silja Weßler
                                        11:30h - 12:00h
                                    
                                
                                
 
                                    
                                        Selective cleavage and novel functions of the Helicobacter pylori oncoprotein CagA in immune cells
Gernot Posselt
                                        11:30h - 11:45h
                                    
                                
                                
 
                                    
                                        SphB1 protease: A key factor in the processing of filamentous hemagglutinin from B. pertussis 
David Jurnečka
                                        11:30h - 11:45h