Keynote opening lecture - Prothrombinase assembly and function- A story of blood and venom
James A. Huntington
20:15h - 21:00h
Opening of the conference
Boris Turk
20:00h - 20:15h
Closing of the conference
Boris Turk
20:10h - 20:40h
Targeting Cathepsin S using sharks and other animals
Christopher Scott
09:30h - 10:00h
Cathepsin V regulates cell cycle progression and histone stability in the nucleus
Roberta Burden
09:30h - 09:45h
Role of cathepsin X and γ-enolase in neuroinflammation: insights from models of multiple sclerosis
Anja Pišlar
09:30h - 09:45h
Lung fibrosis: are cystatin M/E, cathepsin V and legumain newcorners in the game?
Gilles Lalmanach
09:30h - 10:00h
SARS-CoV-2 spike protein affects receptor fates, proteases and the cytoskeleton of neurons
Klaudia Brix
11:30h - 12:00h
Search for Inhibition of Cell Entry of SARS-CoV-2 and Other Viruses
Dušan Turk
11:30h - 12:00h
Cathepsin inhibitors in treatment of SARS-CoV-2 infection
Janko Kos
11:30h - 12:00h
Heterogeneity of neutrophils based on the expression and activity of serine proteases
Paulina Kasperkiewicz-Wasilewska
14:30h - 15:00h
DPP9 is a Positive Regulator of the Unfolded Protein Response
Ruth Geiss-Friedlander
14:30h - 15:00h
Human rhomboid protease RHBDL2 is a suppressor of EGFR signaling in keratinocytes
Kvido Stříšovský
14:30h - 15:00h
Structural Evolution of Multiple Reactive Centers in Kunitz Inhibitors for Targeting Three Proteases
Jaroslav Srp
14:30h - 14:45h
Mechanisms regulating caspase-1-mediated IL-1ß secretion: New insights into a longstanding question
Mohamed Lamkanfi
09:00h - 09:30h
The impact of ECM damage imprint in perpetuating chronic disease
Irit Sagi
09:00h - 09:30h
Small molecule inhibitors of cytotoxic T cell killing as therapeutics for auto-immunity and immunopathology
Joe Trapani
09:00h - 09:30h
Anti-inflammatory effect of cystatins is mediated by mTOR signaling
Nataša Kopitar-Jerala
09:00h - 09:15h
Development of cathepsin B-selective antibody-drug conjugates supported by imaging mass cytometry
Marcin Poręba
11:30h - 12:00h
Characterization of protease activities with conditionally activatable biologics
Olga Vasiljeva
11:30h - 12:00h
Directional Sandwich Panning to Select Inhibitory VHHs Against Fragile Enzymes Including Proteases
Mireille Dumoulin
11:30h - 11:45h
NbE201: A single-domain antibody fragment to inhibit neutrophil elastase and reduce inflammation
Paola Redeghieri
11:30h - 11:45h
Covalent reversible and irreversible compounds for selective detection and inhibition of cathepsin K
Galia Blum
14:30h - 15:00h
Aza-peptide Michael Acceptors as Inhibitors of the Human 20S Proteasome
Özlem Doğan Ekici
14:30h - 15:00h
Prion-Degrading Protease from Aeropyrum pernix K1
Nataša Poklar Ulrih
14:30h - 15:00h
Computational Studies on the Specificity of Substrate-Enzyme interactions based on MEROPS database
Livija Tušar
14:30h - 14:45h
Processing and activation of IL-1 family cytokines by host and pathogen-associated proteases
Seamus J. Martin
09:30h - 10:00h
Miropin: The Yin and Yang of Tannerella forsythia Pathogenicity
Jan Potempa
09:30h - 10:00h
Generating cannibalistic appetites - a new role of P. gingivalis proteases
Juhi Bagaitkar
09:30h - 10:00h
The activator domain in bacterial collagenases unwinds triple-helical collagen
Johann Brandstetter
11:30h - 12:00h
How bacterial HtrA proteases interfere with epithelial host cells and control pathogenesis
Silja Weßler
11:30h - 12:00h
Selective cleavage and novel functions of the Helicobacter pylori oncoprotein CagA in immune cells
Gernot Posselt
11:30h - 11:45h
SphB1 protease: A key factor in the processing of filamentous hemagglutinin from B. pertussis
David Jurnečka
11:30h - 11:45h